PVT1 inhibition stimulates anti-tumor immunity, prevents metastasis, and depletes cancer stem cells in squamous cell carcinoma

Cancer stem cells (CSCs) cause tumor metastasis and immune evasion by as-yet-unknown molecular mechanisms. In the present study, we identify a long noncoding RNA (lncRNA), termed PVT1, which is highly expressed in CSCs and correlated closely with lymph node metastasis of head and neck squamous cell...

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Detalles Bibliográficos
Autores principales: Qin, Zhen, Zhang, Wenbo, Liu, Shuo, Wang, Yujia, Peng, Xin, Jia, Lingfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998619/
https://www.ncbi.nlm.nih.gov/pubmed/36894542
http://dx.doi.org/10.1038/s41419-023-05710-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998619/
https://www.ncbi.nlm.nih.gov/pubmed/36894542
http://dx.doi.org/10.1038/s41419-023-05710-6

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