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Dual roles of TRIM3 in colorectal cancer by retaining p53 in the cytoplasm to decrease its nuclear expression

Colorectal cancer is a very heterogeneous disease caused by the interaction of genetic and environmental factors. P53, as a frequent mutation gene, plays a critical role in the adenoma-carcinoma transition during the tumorous pathological process. Our team discovered TRIM3 as a tumor-associated gene...

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Detalles Bibliográficos
Autores principales: Han, Yang, Lu, Su, Song, Chenlong, Xuan, Yi, Zhang, Meng, Cai, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998637/
https://www.ncbi.nlm.nih.gov/pubmed/36894560
http://dx.doi.org/10.1038/s41420-023-01386-1