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Motor unit number index (MUNIX) loss of 50% occurs in half the time of 50% functional loss according to the D50 disease progression model of ALS

Capturing disease progression in amyotrophic lateral sclerosis (ALS) is challenging and refinement of progression markers is urgently needed. This study introduces new motor unit number index (MUNIX), motor unit size index (MUSIX) and compound muscle action potential (CMAP) parameters called M50, MU...

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Detalles Bibliográficos
Autores principales: Ebersbach, Theresa, Roediger, Annekathrin, Steinbach, Robert, Appelfeller, Martin, Tuemmler, Anke, Stubendorff, Beatrice, Axer, Hubertus, Witte, Otto W., Grosskreutz, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998642/
https://www.ncbi.nlm.nih.gov/pubmed/36894607
http://dx.doi.org/10.1038/s41598-023-30871-x