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Highly purified and functionally stable in vitro expanded allospecific Tr1 cells expressing immunosuppressive graft-homing receptors as new candidates for cell therapy in solid organ transplantation

The development of new strategies based on the use of Tr1 cells has taken relevance to induce long-term tolerance, especially in the context of allogeneic stem cell transplantation. Although Tr1 cells are currently identified by the co-expression of CD49b and LAG-3 and high production of interleukin...

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Detalles Bibliográficos
Autores principales: Arteaga-Cruz, Saúl, Cortés-Hernández, Arimelek, Alvarez-Salazar, Evelyn Katy, Rosas-Cortina, Katya, Aguilera-Sandoval, Christian, Morales-Buenrostro, Luis E., Alberú-Gómez, Josefina M., Soldevila, Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998667/
https://www.ncbi.nlm.nih.gov/pubmed/36911743
http://dx.doi.org/10.3389/fimmu.2023.1062456