A small molecule inhibitor of Notch1 modulates stemness and suppresses breast cancer cell growth

Although breast cancer stem cells (BCSCs) are well characterized, molecularly targeting and eradicating this sub-population remains a challenge in the clinic. Recent studies have explored several signaling pathways that govern stem cell activation: We and others established that the Notch1 signaling...

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Detalles Bibliográficos
Autores principales: Saran, Uttara, Chandrasekaran, Balaji, Tyagi, Ashish, Shukla, Vaibhav, Singh, Amandeep, Sharma, Arun K., Damodaran, Chendil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998682/
https://www.ncbi.nlm.nih.gov/pubmed/36909163
http://dx.doi.org/10.3389/fphar.2023.1150774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998682/
https://www.ncbi.nlm.nih.gov/pubmed/36909163
http://dx.doi.org/10.3389/fphar.2023.1150774

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