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Impact of genetically predicted characterization of mitochondrial DNA quantity and quality on osteoarthritis

Background: Existing studies have indicated that mitochondrial dysfunction may contribute to osteoarthritis (OA) development. However, the causal association between mitochondrial DNA (mtDNA) characterization and OA has not been extensively explored. Methods: Two-sample Mendelian randomization was p...

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Detalles Bibliográficos
Autores principales: Liu, Houpu, Cai, Bingyue, Gong, Ruicheng, Yang, Ye, Wang, Jing, Zhou, Dan, Yu, Min, Li, Yingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998702/
https://www.ncbi.nlm.nih.gov/pubmed/36911418
http://dx.doi.org/10.3389/fgene.2023.1130411