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Cre-dependent ACR2-expressing reporter mouse strain for efficient long-lasting inhibition of neuronal activity

Optogenetics is a powerful tool for manipulating neuronal activity by light illumination with high temporal and spatial resolution. Anion-channelrhodopsins (ACRs) are light-gated anion channels that allow researchers to efficiently inhibit neuronal activity. A blue light-sensitive ACR2 has recently...

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Detalles Bibliográficos
Autores principales: Mukai, Yasutaka, Li, Yan, Nakamura, Akiyo, Fukatsu, Noriaki, Iijima, Daisuke, Abe, Manabu, Sakimura, Kenji, Itoi, Keiichi, Yamanaka, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998869/
https://www.ncbi.nlm.nih.gov/pubmed/36894577
http://dx.doi.org/10.1038/s41598-023-30907-2