Single-cell analysis reveals TLR-induced macrophage heterogeneity and quorum sensing dictate population wide anti-inflammatory feedback in response to LPS

The role of macrophages in controlling tissue inflammation is indispensable to ensure a context-appropriate response to pathogens whilst preventing excessive tissue damage. Their initial response is largely characterized by high production of tumor necrosis factor alpha (TNFα) which primes and attra...

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Detalles Bibliográficos
Autores principales: Tiemeijer, Bart M., Heester, Sebastiaan, Sturtewagen, Ashley Y. W., Smits, Anthal I. P. M., Tel, Jurjen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998924/
https://www.ncbi.nlm.nih.gov/pubmed/36911668
http://dx.doi.org/10.3389/fimmu.2023.1135223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998924/
https://www.ncbi.nlm.nih.gov/pubmed/36911668
http://dx.doi.org/10.3389/fimmu.2023.1135223

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