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Single-cell analysis reveals TLR-induced macrophage heterogeneity and quorum sensing dictate population wide anti-inflammatory feedback in response to LPS
The role of macrophages in controlling tissue inflammation is indispensable to ensure a context-appropriate response to pathogens whilst preventing excessive tissue damage. Their initial response is largely characterized by high production of tumor necrosis factor alpha (TNFα) which primes and attra...
Autores principales: | Tiemeijer, Bart M., Heester, Sebastiaan, Sturtewagen, Ashley Y. W., Smits, Anthal I. P. M., Tel, Jurjen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998924/ https://www.ncbi.nlm.nih.gov/pubmed/36911668 http://dx.doi.org/10.3389/fimmu.2023.1135223 |
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