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RELA tunes innate-like interferon I/III responses in human T cells

In innate immune cells, intracellular sensors such as cGAS-STING stimulate type I/III interferon (IFN) expression, which promotes antiviral defense and immune activation. However, how IFN-I/III expression is controlled in adaptive cells is poorly understood. Here, we identify a transcriptional rheos...

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Detalles Bibliográficos
Autores principales: Jeremiah, Nadia, Ferran, Hermine, Antoniadou, Konstantina, De Azevedo, Kevin, Nikolic, Jovan, Maurin, Mathieu, Benaroch, Philippe, Manel, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998965/
https://www.ncbi.nlm.nih.gov/pubmed/36820829
http://dx.doi.org/10.1084/jem.20220666