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Measurement of selection coefficients from genomic samples of adapting populations by computer modeling

The existing protocols of measuring the selection coefficients of loci neglect linkage effects existing between loci. This protocol is free from this limitation. The protocol inputs a set of DNA sequences at three time points, removes conserved sites, and estimates selection coefficients. If the use...

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Detalles Bibliográficos
Autores principales: Likhachev, Igor V., Rouzine, Igor M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999197/
https://www.ncbi.nlm.nih.gov/pubmed/36871222
http://dx.doi.org/10.1016/j.xpro.2022.101821