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Measurement of selection coefficients from genomic samples of adapting populations by computer modeling
The existing protocols of measuring the selection coefficients of loci neglect linkage effects existing between loci. This protocol is free from this limitation. The protocol inputs a set of DNA sequences at three time points, removes conserved sites, and estimates selection coefficients. If the use...
Autores principales: | Likhachev, Igor V., Rouzine, Igor M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999197/ https://www.ncbi.nlm.nih.gov/pubmed/36871222 http://dx.doi.org/10.1016/j.xpro.2022.101821 |
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