Measurement of extended half-life recombinant FVIII molecules: In vitro and ex vivo evidence of relevant assay discrepancies

BACKGROUND: Extended half-life recombinant FVIII products (EHL-rFVIIIs) have been engineered to improve the pharmacokinetic profile of FVIII, enabling better hemostatic protection with a reduced number of injections in persons with hemophilia. Previous studies showed several discrepancies in FVIII a...

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Detalles Bibliográficos
Autores principales: Lancellotti, Stefano, Sacco, Monica, Tardugno, Maira, Mancuso, Maria Elisa, De Cristofaro, Raimondo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999201/
https://www.ncbi.nlm.nih.gov/pubmed/36908765
http://dx.doi.org/10.1016/j.rpth.2023.100070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999201/
https://www.ncbi.nlm.nih.gov/pubmed/36908765
http://dx.doi.org/10.1016/j.rpth.2023.100070

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