Pyrazole-based lamellarin O analogues: synthesis, biological evaluation and structure–activity relationships

A library of pyrazole-based lamellarin O analogues was synthesized from easily accessible 3(5)-aryl-1H-pyrazole-5(3)-carboxylates which were subsequently modified by bromination, N-alkylation and Pd-catalysed Suzuki cross-coupling reactions. Synthesized ethyl and methyl 3,4-diaryl-1-(2-aryl-2-oxoeth...

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Detalles Bibliográficos
Autores principales: Dzedulionytė, Karolina, Fuxreiter, Nina, Schreiber-Brynzak, Ekaterina, Žukauskaitė, Asta, Šačkus, Algirdas, Pichler, Verena, Arbačiauskienė, Eglė
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999251/
https://www.ncbi.nlm.nih.gov/pubmed/36909769
http://dx.doi.org/10.1039/d3ra00972f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999251/
https://www.ncbi.nlm.nih.gov/pubmed/36909769
http://dx.doi.org/10.1039/d3ra00972f

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