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Active Nuclear Import of Mammalian Cell-Expressible DNA Origami

[Image: see text] DNA origami enables the creation of complex 3D shapes from genetic material. Future uses could include the delivery of genetic instructions to cells, but nuclear import remains a major barrier to gene delivery due to the impermeability of the nuclear membrane. Here we realize activ...

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Detalles Bibliográficos
Autores principales: Liedl, Anna, Grießing, Johanna, Kretzmann, Jessica A., Dietz, Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999407/
https://www.ncbi.nlm.nih.gov/pubmed/36828394
http://dx.doi.org/10.1021/jacs.2c12733