Oridonin alleviates the inhibitory effect of lipopolysaccharide on the proliferation and osteogenic potential of periodontal ligament stem cells by inhibiting endoplasmic reticulum stress and NF-κB/NLRP3 inflammasome signaling

BACKGROUND: The aim of this study was to investigate the protective effect and mechanism of oridonin in an in vitro lipopolysaccharide (LPS)-induced human periodontal ligament stem cells (hPDLSCs) model of periodontitis. METHODS: Primary hPDLSCs were isolated and cultured, and then the expression of...

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Detalles Bibliográficos
Autores principales: Jiang, Junhao, Zhang, Nong, Song, Haibo, Yang, Ya, Li, Juan, Hu, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999511/
https://www.ncbi.nlm.nih.gov/pubmed/36894905
http://dx.doi.org/10.1186/s12903-023-02827-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999511/
https://www.ncbi.nlm.nih.gov/pubmed/36894905
http://dx.doi.org/10.1186/s12903-023-02827-0

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