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Oridonin alleviates the inhibitory effect of lipopolysaccharide on the proliferation and osteogenic potential of periodontal ligament stem cells by inhibiting endoplasmic reticulum stress and NF-κB/NLRP3 inflammasome signaling

BACKGROUND: The aim of this study was to investigate the protective effect and mechanism of oridonin in an in vitro lipopolysaccharide (LPS)-induced human periodontal ligament stem cells (hPDLSCs) model of periodontitis. METHODS: Primary hPDLSCs were isolated and cultured, and then the expression of...

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Detalles Bibliográficos
Autores principales:	Jiang, Junhao, Zhang, Nong, Song, Haibo, Yang, Ya, Li, Juan, Hu, Xiaoli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999511/ https://www.ncbi.nlm.nih.gov/pubmed/36894905 http://dx.doi.org/10.1186/s12903-023-02827-0

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