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A novel rhein-huprine hybrid ameliorates disease-modifying properties in preclinical mice model of Alzheimer’s disease exacerbated with high fat diet

BACKGROUND: Alzheimer’s disease (AD) is characterized by a polyetiological origin. Despite the global burden of AD and the advances made in AD drug research and development, the cure of the disease remains elusive, since any developed drug has demonstrated effectiveness to cure AD. Strikingly, an in...

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Detalles Bibliográficos
Autores principales: Espinosa-Jiménez, Triana, Cano, Amanda, Sánchez-López, Elena, Olloquequi, Jordi, Folch, Jaume, Bulló, Mònica, Verdaguer, Ester, Auladell, Carme, Pont, Caterina, Muñoz-Torrero, Diego, Parcerisas, Antoni, Camins, Antoni, Ettcheto, Miren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999531/
https://www.ncbi.nlm.nih.gov/pubmed/36895036
http://dx.doi.org/10.1186/s13578-023-01000-y