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A novel rhein-huprine hybrid ameliorates disease-modifying properties in preclinical mice model of Alzheimer’s disease exacerbated with high fat diet
BACKGROUND: Alzheimer’s disease (AD) is characterized by a polyetiological origin. Despite the global burden of AD and the advances made in AD drug research and development, the cure of the disease remains elusive, since any developed drug has demonstrated effectiveness to cure AD. Strikingly, an in...
Autores principales: | Espinosa-Jiménez, Triana, Cano, Amanda, Sánchez-López, Elena, Olloquequi, Jordi, Folch, Jaume, Bulló, Mònica, Verdaguer, Ester, Auladell, Carme, Pont, Caterina, Muñoz-Torrero, Diego, Parcerisas, Antoni, Camins, Antoni, Ettcheto, Miren |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999531/ https://www.ncbi.nlm.nih.gov/pubmed/36895036 http://dx.doi.org/10.1186/s13578-023-01000-y |
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