In vivo toxicity evaluation of tumor targeted glycol chitosan nanoparticles in healthy mice: repeated high-dose of glycol chitosan nanoparticles potentially induce cardiotoxicity

BACKGROUND: Glycol chitosan nanoparticles (CNPs) have emerged as an effective drug delivery system for cancer diagnosis and treatment. Although they have great biocompatibility owing to biodegradable chemical structure and low immunogenicity, sufficient information on in vivo toxicity to understand...

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Detalles Bibliográficos
Autores principales: Chang, Hyeyoun, Yhee, Ji Young, Jeon, Sangmin, Shim, Man Kyu, Yoon, Hong Yeol, Lee, Sangmin, Kim, Kwangmeyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999623/
https://www.ncbi.nlm.nih.gov/pubmed/36894943
http://dx.doi.org/10.1186/s12951-023-01824-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999623/
https://www.ncbi.nlm.nih.gov/pubmed/36894943
http://dx.doi.org/10.1186/s12951-023-01824-3

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