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APRIL: A double-blind, placebo-controlled, randomized, Phase Ib/IIa clinical study of ApTOLL for the treatment of acute ischemic stroke

In the reperfusion era, a new paradigm of treating patients with endovascular treatment (EVT) and neuroprotective drugs is emerging as a promising therapeutic option for patients with acute ischemic stroke (AIS). In this context, ApTOLL, a Toll-like receptor 4 (TLR4) antagonist with proven neuroprot...

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Detalles Bibliográficos
Autores principales: Hernández-Jiménez, Macarena, Abad-Santos, Francisco, Cotgreave, Ian, Gallego, Jaime, Jilma, Bernd, Flores, Alan, Jovin, Tudor G., Vivancos, José, Molina, Carlos A., Montaner, Joan, Casariego, Joaquín, Dalsgaard, Mads, Hernández-Pérez, María, Liebeskind, David S., Cobo, Erik, Ribo, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999729/
https://www.ncbi.nlm.nih.gov/pubmed/36908619
http://dx.doi.org/10.3389/fneur.2023.1127585