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Microbiota alters the metabolome in an age- and sex- dependent manner in mice

Commensal bacteria are major contributors to mammalian metabolism. We used liquid chromatography mass spectrometry to study the metabolomes of germ-free, gnotobiotic, and specific-pathogen-free mice, while also evaluating the influence of age and sex on metabolite profiles. Microbiota modified the m...

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Detalles Bibliográficos
Autores principales: Brown, Kirsty, Thomson, Carolyn A., Wacker, Soren, Drikic, Marija, Groves, Ryan, Fan, Vina, Lewis, Ian A., McCoy, Kathy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008592/
https://www.ncbi.nlm.nih.gov/pubmed/36906623
http://dx.doi.org/10.1038/s41467-023-37055-1