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Transcription factors in megakaryocytes and platelets

Transcription factors bind promoter or regulatory sequences of a gene to regulate its rate of transcription. However, they are also detected in anucleated platelets. The transcription factors RUNX1, GATA1, STAT3, NFκB, and PPAR have been widely reported to play key roles in the pathophysiology of pl...

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Detalles Bibliográficos
Autores principales: Yuan, Hengjie, Liu, Yafan, Zhang, Jianning, Dong, Jing-fei, Zhao, Zilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034027/
https://www.ncbi.nlm.nih.gov/pubmed/36969155
http://dx.doi.org/10.3389/fimmu.2023.1140501