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Hypoxia‐Inducible Factor‐2α Signaling in the Skeletal System

Hypoxia‐inducible factors (HIFs) are oxygen‐dependent heterodimeric transcription factors that mediate molecular responses to reductions in cellular oxygen (hypoxia). HIF signaling involves stable HIF‐β subunits and labile, oxygen‐sensitive HIF‐α subunits. Under hypoxic conditions, the HIF‐α subunit...

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Detalles Bibliográficos
Autores principales: Mendoza, Sarah V, Genetos, Damian C, Yellowley, Clare E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097641/
https://www.ncbi.nlm.nih.gov/pubmed/37065626
http://dx.doi.org/10.1002/jbm4.10733