Cargando…

Ultra-rapid Idylla™ EGFR mutation screening followed by next-generation sequencing: An integrated solution to molecular diagnosis of non-small cell lung cancer

BACKGROUND: Rapid profiling of the EGFR mutations is crucial to help clinicians choose the optimal treatment for patients with advanced/metastatic Non-Small Cell Lung Cancer (NSCLC). Unfortunately, current diagnostic techniques, including ARMS-PCR and NGS, generally require several days to deliver f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qiu, Tian, Zhang, Fanshuang, Zheng, Bo, Feng, Zitong, Li, Weihua, Zeng, Hua, Chu, Lixia, Ying, Jianming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102514/ https://www.ncbi.nlm.nih.gov/pubmed/37064089 http://dx.doi.org/10.3389/fonc.2023.1064487

Ejemplares similares

Performance of Ultra-Rapid Idylla™ EGFR Mutation Test in Non-Small-Cell Lung Cancer and Its Potential at Clinical Molecular Screening
por: Suda, Kenichi, et al.
Publicado: (2023)

Utility of Select Gene Mutation Detection in Tumors by the Idylla Rapid Multiplex PCR Platform in Comparison to Next-Generation Sequencing
por: Nkosi, Dingani, et al.
Publicado: (2022)

Testing EGFR with Idylla on Cytological Specimens of Lung Cancer: A Review
por: Caputo, Alessandro, et al.
Publicado: (2021)

Contribution of the Idylla(TM) System to Improving the Therapeutic Care of Patients with NSCLC through Early Screening of EGFR Mutations
por: Petiteau, Constance, et al.
Publicado: (2021)

Efficient Lung Cancer Molecular Diagnostics by Combining Next Generation Sequencing with Reflex Idylla Genefusion Assay Testing
por: Nkosi, Dingani, et al.
Publicado: (2023)

Evaluation of the Idylla ctEGFR mutation assay to detect EGFR mutations in plasma from patients with non-small cell lung cancers
por: Gilson, Pauline, et al.
Publicado: (2021)

Short report: Performance evaluation of the Idylla™ KRAS and EGFR mutation tests on paraffin-embedded cytological NSCLC samples
por: Offerman, Saskia, et al.
Publicado: (2021)

Detection of KRAS mutations in liquid biopsies from metastatic colorectal cancer patients using droplet digital PCR, Idylla, and next generation sequencing
por: Holm, Matilda, et al.
Publicado: (2020)

Subjecting appropriate lung adenocarcinoma samples to next‐generation sequencing‐based molecular testing: challenges and possible solutions
por: Li, Weihua, et al.
Publicado: (2018)

High MAF of EGFR mutations and high ratio of T790M sensitizing mutations in ctDNA predict better third‐generation TKI outcomes
por: Li, Yan, et al.
Publicado: (2020)

Not enough can be enough: feasibility of the Idylla EGFR mutation test when reuse of stained tissue slides is the only option available
por: Ercolani, Cristiana, et al.
Publicado: (2022)

Diagnostic performance of Idylla MSI test in colorectal cancer biopsies
por: Ukkola, Iiris, et al.
Publicado: (2023)

Next-Generation Sequencing Reveals High Uncommon EGFR Mutations and Tumour Mutation Burden in a Subgroup of Lung Cancer Patients
por: Guo, Gang, et al.
Publicado: (2021)

Improving Time-to-Treatment for Advanced Non-Small Cell Lung Cancer Patients through Faster Single Gene EGFR Testing Using the Idylla™ EGFR Testing Platform
por: Banyi, Norbert, et al.
Publicado: (2022)

Clinical performance evaluation of the Idylla™ EGFR Mutation Test on formalin-fixed paraffin-embedded tissue of non-small cell lung cancer
por: Delgado-García, Mercedes, et al.
Publicado: (2020)

Navigating the Rapids: The Development of Regulated Next-Generation Sequencing-Based Clinical Trial Assays and Companion Diagnostics
por: Pant, Saumya, et al.
Publicado: (2014)

Detection of microsatellite instability with Idylla MSI assay in colorectal and endometrial cancer
por: Ukkola, Iiris, et al.
Publicado: (2021)

Next-generation sequencing-based detection in a breast MMPMN patient with EGFR T790M mutation: a rare case report and literature review
por: Lv, Huiyun, et al.
Publicado: (2023)

Rapid BRAF mutation tests in patients with advanced melanoma: comparison of immunohistochemistry, Droplet Digital PCR, and the Idylla Mutation Platform
por: Bisschop, Cornelis, et al.
Publicado: (2018)

Melanoma Immunotherapy: Next-Generation Biomarkers
por: Hogan, Sabrina A., et al.
Publicado: (2018)

Prevalence and characteristics of PIK3CA mutation in mismatch repair-deficient colorectal cancer
por: Li, Weihua, et al.
Publicado: (2020)

Rethink of EGFR in Cancer With Its Kinase Independent Function on Board
por: Thomas, Rintu, et al.
Publicado: (2019)

Scalable Newborn Screening Solutions: Bioinformatics and Next-Generation Sequencing
por: Ruiz-Schultz, Nicole, et al.
Publicado: (2021)

Heterogeneity of resistant mechanisms in an EGFR-TKI relapsed patient with EGFR amplification and response to nimotuzumab: A case report
por: Li, Yan, et al.
Publicado: (2022)

EGFR/FOXO3A/LXR-α Axis Promotes Prostate Cancer Proliferation and Metastasis and Dual-Targeting LXR-α/EGFR Shows Synthetic Lethality
por: Chen, Tingting, et al.
Publicado: (2020)

Genomics of Acute Myeloid Leukemia: The Next Generation
por: Riva, Laura, et al.
Publicado: (2012)

Next-Generation Sequencing of Disseminated Tumor Cells
por: Møller, Elen K., et al.
Publicado: (2013)

Next-Generation in vivo Modeling of Human Cancers
por: Gargiulo, Gaetano
Publicado: (2018)

Nanobodies: Next Generation of Cancer Diagnostics and Therapeutics
por: Yang, Emily Y., et al.
Publicado: (2020)

Advanced Non-small Cell Lung Cancer: EGFR Mutation Analysis Using Pyrosequencing and the Fully Automated qPCR-Based Idylla(TM) System
por: Boustany, Youssra, et al.
Publicado: (2023)

Acquired resistance to third-generation EGFR-TKIs and emerging next-generation EGFR inhibitors
por: Du, Xiaojing, et al.
Publicado: (2021)

Detection of EGFR Mutations in Cerebrospinal Fluid of EGFR-Mutant Lung Adenocarcinoma With Brain Metastases
por: Shi, Liang, et al.
Publicado: (2021)

Cancer Immunotherapy and Next-Generation Clinical Immune Assessment
por: Ma, Chao, et al.
Publicado: (2014)

Next-Generation Cancer Immunotherapy Targeting Glypican-3
por: Shimizu, Yasuhiro, et al.
Publicado: (2019)

Editorial: Next generation staging in head and neck cancers
por: Iyer, N. Gopalakrishna, et al.
Publicado: (2022)

Optimization of EGFR mutation detection by the fully-automated qPCR-based Idylla system on tumor tissue from patients with non-small cell lung cancer
por: Ilie, Marius, et al.
Publicado: (2017)

Development of EGFR TKIs and Options to Manage Resistance of Third-Generation EGFR TKI Osimertinib: Conventional Ways and Immune Checkpoint Inhibitors
por: Wu, Leilei, et al.
Publicado: (2020)

Epithelioid glioblastoma exhibits a heterogeneous molecular feature: A targeted next-generation sequencing study
por: Pan, Rui, et al.
Publicado: (2022)

Dynamic cfDNA Analysis by NGS in EGFR T790M-Positive Advanced NSCLC Patients Failed to the First-Generation EGFR-TKIs
por: Ma, Li, et al.
Publicado: (2021)

Next Generation Sequencing in metastatic castrate-resistant prostate cancer
por: Adashek, Jacob J., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_p1ahm0dbjhlccin6m6531ieg56