A universal fluorescence polarization high throughput screening assay to target the SAM-binding sites of SARS-CoV-2 and other viral methyltransferases

SARS-CoV-2 has caused a global pandemic with significant humanity and economic loss since 2020. Currently, only limited options are available to treat SARS-CoV-2 infections for vulnerable populations. In this study, we report a universal fluorescence polarization (FP)-based high throughput screening...

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Detalles Bibliográficos
Autores principales: Samrat, Subodh Kumar, Bashir, Qamar, Zhang, Ran, Huang, Yiding, Liu, Yuchen, Wu, Xiangmeng, Brown, Tyler, Wang, Wei, Zheng, Y. George, Zhang, Qing-Yu, Chen, Yin, Li, Zhong, Li, Hongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Antimicrobial Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165934/
https://www.ncbi.nlm.nih.gov/pubmed/37060263
http://dx.doi.org/10.1080/22221751.2023.2204164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165934/
https://www.ncbi.nlm.nih.gov/pubmed/37060263
http://dx.doi.org/10.1080/22221751.2023.2204164

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