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Thyroid hormone modulates hyperoxic neonatal lung injury and mitochondrial function

Mitochondrial dysfunction at birth predicts bronchopulmonary dysplasia (BPD) in extremely low–birth weight (ELBW) infants. Recently, nebulized thyroid hormone (TH), given as triiodothyronine (T3), was noted to decrease pulmonary fibrosis in adult animals through improved mitochondrial function. In t...

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Detalles Bibliográficos
Autores principales: Vamesu, Bianca M., Nicola, Teodora, Li, Rui, Hazra, Snehashis, Matalon, Sadis, Kaminski, Naftali, Ambalavanan, Namasivayam, Kandasamy, Jegen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243814/
https://www.ncbi.nlm.nih.gov/pubmed/36917181
http://dx.doi.org/10.1172/jci.insight.160697