DIPG-43. CLINICAL AND MOLECULAR CHARACTERISTIC OF A NEW SUBTYPE OF DMG, H3K27-ALTERED WITH MAPK-ACTIVATING CO-DRIVER MUTATIONS

Diffuse midline gliomas (DMG) represent a big challenge in neuro-oncology. These tumors occur more frequently in children and are presently incurable. They are characterized by a K27M substitution in H3.1 or H3.3 histone tail or the overexpression of EZHIP (EZH Inhibitory Protein). These three alter...

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Detalles Bibliográficos
Autores principales: Auffret, Lucie, Ajlil, Yassine, Kergrohen, Thomas, Tauziède-Espariat, Arnault, Puiseux, Chloé, Riffaud, Laurent, Picca, Alberto, Touat, Medhi, Sanson, Marc, Beccaria, Kevin, Blauwblomme, Thomas, Dangouloff-Ros, Volodia, Boddaert, Nathalie, Varlet, Pacale, Debily, Marie-Anne, Grill, Jacques, Castel, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Diffuse Intrinsic Pontine Glioma/Diffuse Midline Gliomas - DPIG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260141/
http://dx.doi.org/10.1093/neuonc/noad073.090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260141/
http://dx.doi.org/10.1093/neuonc/noad073.090

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