Inhibition of the voltage-gated potassium channel Kv1.5 by hydrogen sulfide attenuates remodeling through S-nitrosylation-mediated signaling

The voltage-gated K(+) channel plays a key role in atrial excitability, conducting the ultra-rapid rectifier K(+) current (I(Kur)) and contributing to the repolarization of the atrial action potential. In this study, we examine its regulation by hydrogen sulfide (H(2)S) in HL-1 cardiomyocytes and in...

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Detalles Bibliográficos
Autores principales: Al-Owais, Moza M., Hettiarachchi, Nishani T., Dallas, Mark L., Scragg, Jason L., Lippiat, Jonathan D., Holden, Arun V., Steele, Derek S., Peers, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279668/
https://www.ncbi.nlm.nih.gov/pubmed/37336943
http://dx.doi.org/10.1038/s42003-023-05016-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279668/
https://www.ncbi.nlm.nih.gov/pubmed/37336943
http://dx.doi.org/10.1038/s42003-023-05016-5

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