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Partial sequence identity in a 25-nucleotide long element is sufficient for transcriptional adaptation in the Caenorhabditis elegans act-5/act-3 model

Genetic robustness can be achieved via several mechanisms including transcriptional adaptation (TA), a sequence similarity-driven process whereby mutant mRNA degradation products modulate, directly or indirectly, the expression of so-called adapting genes. To identify the sequences required for this...

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Detalles Bibliográficos
Autores principales: Welker, Jordan M., Serobyan, Vahan, Zaker Esfahani, Elhamalsadat, Stainier, Didier Y. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310345/
https://www.ncbi.nlm.nih.gov/pubmed/37384903
http://dx.doi.org/10.1371/journal.pgen.1010806