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Pharmacological inhibition of demethylzeylasteral on JAK-STAT signaling ameliorates vitiligo
BACKGROUND: The activation of CD8(+) T cells and their trafficking to the skin through JAK-STAT signaling play a central role in the development of vitiligo. Thus, targeting this key disease pathway with innovative drugs is an effective strategy for treating vitiligo. Natural products isolated from...
Autores principales: | Chang, Yuqian, Kang, Pan, Cui, Tingting, Guo, Weinan, Zhang, Weigang, Du, Pengran, Yi, Xiuli, Guo, Sen, Gao, Tianwen, Li, Chunying, Li, Shuli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318684/ https://www.ncbi.nlm.nih.gov/pubmed/37403086 http://dx.doi.org/10.1186/s12967-023-04293-2 |
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