Substrate displacement of CK1 C-termini regulates kinase specificity

CK1 kinases participate in many signaling pathways; how these enzymes are regulated is therefore of significant biological consequence. CK1s autophosphorylate their C-terminal non-catalytic tails, and eliminating these modifications increases substrate phosphorylation in vitro, suggesting that the a...

Descripción completa

Detalles Bibliográficos
Autores principales: Cullati, Sierra N., Akizuki, Kazutoshi, Chen, Jun-Song, Gould, Kathleen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327203/
https://www.ncbi.nlm.nih.gov/pubmed/37425826
http://dx.doi.org/10.1101/2023.06.30.547285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327203/
https://www.ncbi.nlm.nih.gov/pubmed/37425826
http://dx.doi.org/10.1101/2023.06.30.547285

Ejemplares similares