SHH PATHWAY ACTIVATION DRIVES MALIGNANT TRANSFORMATION IN A SUBSET OF MPNSTS AND IS A POTENTIAL THERAPEUTIC TARGET

BTFC travel award recipient Malignant peripheral nerve sheath tumors (MPNSTs) are highly aggressive Schwann-cell derived sarcomas and the leading cause of mortality in Neurofibromatosis Type 1. The molecular pathways driving malignant transformation is not well understood. In this study, we leverage...

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Detalles Bibliográficos
Autores principales: Suppiah, Suganth, Mansouri, Sheila, Liu, Jeff, Patel, Vikas, Bunda, Severa, Zadeh, Gelareh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Oral Abstract Presentations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337529/
http://dx.doi.org/10.1093/noajnl/vdad071.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337529/
http://dx.doi.org/10.1093/noajnl/vdad071.005

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