SALL4 as an indicator for the diagnosis of hepatoid carcinoma of the ovary: A case report and literature review

KEY CLINICAL MESSAGE: Primary HCO is a rare, aggressive ovarian malignant tumor, morphologically resembling HCC. SALL4 can be adopted to differentiate HCO from HCC. The serum AFP and CA125 rather than HE4 can be employed as possible biomarkers to track treatment and monitor recurrence. ABSTRACT: We...

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Detalles Bibliográficos
Autores principales: Li, Jiana, Wu, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387514/
https://www.ncbi.nlm.nih.gov/pubmed/37529124
http://dx.doi.org/10.1002/ccr3.7706
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author Li, Jiana
Wu, Xiaohua
author_facet Li, Jiana
Wu, Xiaohua
author_sort Li, Jiana
collection PubMed
description KEY CLINICAL MESSAGE: Primary HCO is a rare, aggressive ovarian malignant tumor, morphologically resembling HCC. SALL4 can be adopted to differentiate HCO from HCC. The serum AFP and CA125 rather than HE4 can be employed as possible biomarkers to track treatment and monitor recurrence. ABSTRACT: We report a case of a postmenopausal woman presenting with lower abdominal pain and vaginal bleeding. She went through a maximal debulking surgery, and the pathological biopsy revealed hepatoid carcinoma of the ovary (HCO). Immunohistochemical assay demonstrates SALL4 as an indicator to differentiate HCO from hepatocellular carcinoma (HCC).
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spelling pubmed-103875142023-08-01 SALL4 as an indicator for the diagnosis of hepatoid carcinoma of the ovary: A case report and literature review Li, Jiana Wu, Xiaohua Clin Case Rep Case Report KEY CLINICAL MESSAGE: Primary HCO is a rare, aggressive ovarian malignant tumor, morphologically resembling HCC. SALL4 can be adopted to differentiate HCO from HCC. The serum AFP and CA125 rather than HE4 can be employed as possible biomarkers to track treatment and monitor recurrence. ABSTRACT: We report a case of a postmenopausal woman presenting with lower abdominal pain and vaginal bleeding. She went through a maximal debulking surgery, and the pathological biopsy revealed hepatoid carcinoma of the ovary (HCO). Immunohistochemical assay demonstrates SALL4 as an indicator to differentiate HCO from hepatocellular carcinoma (HCC). John Wiley and Sons Inc. 2023-07-30 /pmc/articles/PMC10387514/ /pubmed/37529124 http://dx.doi.org/10.1002/ccr3.7706 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Report
Li, Jiana
Wu, Xiaohua
SALL4 as an indicator for the diagnosis of hepatoid carcinoma of the ovary: A case report and literature review
title SALL4 as an indicator for the diagnosis of hepatoid carcinoma of the ovary: A case report and literature review
title_full SALL4 as an indicator for the diagnosis of hepatoid carcinoma of the ovary: A case report and literature review
title_fullStr SALL4 as an indicator for the diagnosis of hepatoid carcinoma of the ovary: A case report and literature review
title_full_unstemmed SALL4 as an indicator for the diagnosis of hepatoid carcinoma of the ovary: A case report and literature review
title_short SALL4 as an indicator for the diagnosis of hepatoid carcinoma of the ovary: A case report and literature review
title_sort sall4 as an indicator for the diagnosis of hepatoid carcinoma of the ovary: a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10387514/
https://www.ncbi.nlm.nih.gov/pubmed/37529124
http://dx.doi.org/10.1002/ccr3.7706
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AT wuxiaohua sall4asanindicatorforthediagnosisofhepatoidcarcinomaoftheovaryacasereportandliteraturereview

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