Risk-reducing surgery for individuals with cancer-predisposing germline pathogenic variants and no personal cancer history: a review of current UK guidelines

Identifying healthy carriers of germline pathogenic variants in high penetrance cancer susceptibility genes offers the potential for risk-reducing surgery. The NHS England National Genomic Test Directory offers germline and somatic testing to patients with certain cancers or rare and inherited disea...

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Detalles Bibliográficos
Autores principales: McCarthy, Rebecca L., Copson, Ellen, Tapper, William, Bolton, Helen, Mirnezami, Alex H., O’Neill, J. Robert, Patel, Nimesh N., Tischkowitz, Marc, Cutress, Ramsey I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403612/
https://www.ncbi.nlm.nih.gov/pubmed/37258796
http://dx.doi.org/10.1038/s41416-023-02296-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403612/
https://www.ncbi.nlm.nih.gov/pubmed/37258796
http://dx.doi.org/10.1038/s41416-023-02296-w

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