CFTR dysfunction in smooth muscle drives TGFβ dependent airway hyperreactivity

BACKGROUND: The primary underlying defect in cystic fibrosis (CF) is disrupted ion transport in epithelia throughout the body. It is unclear if symptoms such as airway hyperreactivity (AHR) and increased airway smooth muscle (ASM) volume in people with CF are due to inherent abnormalities in smooth...

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Detalles Bibliográficos
Autores principales: Kramer, Elizabeth L., Hudock, Kristin M., Davidson, Cynthia R., Clancy, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416378/
https://www.ncbi.nlm.nih.gov/pubmed/37568151
http://dx.doi.org/10.1186/s12931-023-02495-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416378/
https://www.ncbi.nlm.nih.gov/pubmed/37568151
http://dx.doi.org/10.1186/s12931-023-02495-2

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