Distinct transcriptional responses to fludioxonil in Aspergillus fumigatus and its ΔtcsC and Δskn7 mutants reveal a crucial role for Skn7 in the cell wall reorganizations triggered by this antifungal

BACKGROUND: Aspergillus fumigatus is a major fungal pathogen that causes severe problems due to its increasing resistance to many therapeutic agents. Fludioxonil is a compound that triggers a lethal activation of the fungal-specific High Osmolarity Glycerol pathway. Its pronounced antifungal activit...

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Detalles Bibliográficos
Autores principales: Schruefer, Sebastian, Pschibul, Annica, Wong, Sarah Sze Wah, Sae-Ong, Tongta, Wolf, Thomas, Schäuble, Sascha, Panagiotou, Gianni, Brakhage, Axel A., Aimanianda, Vishukumar, Kniemeyer, Olaf, Ebel, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647056/
https://www.ncbi.nlm.nih.gov/pubmed/37964194
http://dx.doi.org/10.1186/s12864-023-09777-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647056/
https://www.ncbi.nlm.nih.gov/pubmed/37964194
http://dx.doi.org/10.1186/s12864-023-09777-5

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