Third-generation rabies viral vectors have low toxicity and improved efficiency as retrograde labeling tools

In this issue of Cell Reports Methods, Jin et al. report the generation and validation of a rabies variant, RVΔL, for projection-based neuronal labeling. RVΔL shows little toxicity in vivo and has an improved growth advantage over another variant, RVΔGL, making it a useful tool for a wide variety of...

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Detalles Bibliográficos
Autor principal: Schwarz, Lindsay A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694576/
https://www.ncbi.nlm.nih.gov/pubmed/37989082
http://dx.doi.org/10.1016/j.crmeth.2023.100646