NKG2A inhibits TH2 cell effector function in vitro

BACKGROUND: We previously reported that NKG2A, a key inhibitory ligand for HLA-E, is expressed on activated TH2 but not TH1 cells. Here we measured cytokine expression in human ex vivo TH2 cells upon activation with anti-CD3/28 and challenge with an NKG2A-specific agonist. METHODS: TH2 cells were pu...

Descripción completa

Detalles Bibliográficos
Autores principales: Freishtat, Robert J, Mojgani, Bahar, Nazemzadeh, Maryam, Nagaraju, Kanneboyina, Hoffman, Eric P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174509/
https://www.ncbi.nlm.nih.gov/pubmed/17927829
http://dx.doi.org/10.1186/1471-2466-7-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174509/
https://www.ncbi.nlm.nih.gov/pubmed/17927829
http://dx.doi.org/10.1186/1471-2466-7-14

Ejemplares similares