Interaction of deoxycholate with the sodium channel of squid axon membranes

Deoxycholate can react with sodium channels with a high potency. The apparent dissociation constant for the saturable binding reaction is 2 microM at 8 degrees C, and the heat of reaction is approximately -7 kcal/mol. Four independent test with Na-free media, K-free media, tetrodotoxin, and pancuron...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1980
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228597/
https://www.ncbi.nlm.nih.gov/pubmed/6252280