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Repetitive N-WASP–Binding Elements of the Enterohemorrhagic Escherichia coli Effector EspF(U) Synergistically Activate Actin Assembly

Enterohemorrhagic Escherichia coli (EHEC) generate F-actin–rich adhesion pedestals by delivering effector proteins into mammalian cells. These effectors include the translocated receptor Tir, along with EspF(U), a protein that associates indirectly with Tir and contains multiple peptide repeats that...

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Detalles Bibliográficos
Autores principales: Campellone, Kenneth G., Cheng, Hui-Chun, Robbins, Douglas, Siripala, Anosha D., McGhie, Emma J., Hayward, Richard D., Welch, Matthew D., Rosen, Michael K., Koronakis, Vassilis, Leong, John M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567903/
https://www.ncbi.nlm.nih.gov/pubmed/18974829
http://dx.doi.org/10.1371/journal.ppat.1000191