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Aldosterone-induced TGF-β(1) Expression is Regulated by Mitogen-Activated Protein Kinases and Activator Protein-1 in Mesangial Cells

Aldosterone has been shown to stimulate renal TGF-β(1) expression. However, the mechanisms for aldosterone-induced TGF-β(1) expression have not been clearly determined in mesangial cells. We examined the role of extracellular-signal regulated kinase 1 and 2 (ERK1/2), c-Jun N-terminal kinase (JNK) an...

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Detalles Bibliográficos
Autores principales: Han, Jeong-Sun, Choi, Bum-Soon, Yang, Chul-Woo, Kim, Yong-Soo
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633178/
https://www.ncbi.nlm.nih.gov/pubmed/19194552
http://dx.doi.org/10.3346/jkms.2009.24.S1.S195