The impact of negative selection on thymocyte migration in the medulla

Developing thymocytes are screened for self-reactivity before exiting the thymus, but how thymocytes scan the medulla for self-antigens is unclear. Using two-photon microscopy, we observed that medullary thymocytes migrated rapidly and made frequent, transient contacts with dendritic cells. In the p...

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Detalles Bibliográficos
Autores principales: Le Borgne, Marie, Ladi, Ena, Dzhagalov, Ivan, Herzmark, Paul, Liao, Ying Fang, Chakraborty, Arup K., Robey, Ellen A.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2793676/
https://www.ncbi.nlm.nih.gov/pubmed/19543275
http://dx.doi.org/10.1038/ni.1761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2793676/
https://www.ncbi.nlm.nih.gov/pubmed/19543275
http://dx.doi.org/10.1038/ni.1761

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