Phylogenetics Applied to Genotype/Phenotype Association and Selection Analyses with Sequence Data from Angptl4 in Humans

Genotype/phenotype association analyses (Treescan) with plasma lipid levels and functional site prediction methods (TreeSAAP and PolyPhen) were performed using sequence data for ANGPTL4 from 3,551 patients in the Dallas Heart Study. Biological assays of rare variants in phenotypic tails and results...

Descripción completa

Detalles Bibliográficos
Autores principales: Maxwell, Taylor J., Bendall, Matthew L., Staples, Jeffrey, Jarvis, Todd, Crandall, Keith A.
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821009/
https://www.ncbi.nlm.nih.gov/pubmed/20162021
http://dx.doi.org/10.3390/ijms11010370