GSK3β Inhibitor Peptide Protects Mice from LPS-induced Endotoxin Shock

BACKGROUND: Glycogen synthase kinase 3β (GSK3β) is a ubiquitous serine/threonine kinase that is regulated by serine phosphorylation at 9. Recent studies have reported the beneficial effects of a number of the pharmacological GSK3β inhibitors in rodent models of septic shock. Since most of the GSK3β...

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Detalles Bibliográficos
Autores principales: Ko, Ryeojin, Jang, Hyun Duk, Lee, Soo Young
Formato: Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902676/
https://www.ncbi.nlm.nih.gov/pubmed/20631880
http://dx.doi.org/10.4110/in.2010.10.3.99