Validation of a constraint-based model of Pichia pastoris metabolism under data scarcity
BACKGROUND: Constraint-based models enable structured cellular representations in which intracellular kinetics are circumvented. These models, combined with experimental data, are useful analytical tools to estimate the state exhibited (the phenotype) by the cells at given pseudo-steady conditions....
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936294/ https://www.ncbi.nlm.nih.gov/pubmed/20716335 http://dx.doi.org/10.1186/1752-0509-4-115 |