Epigenetic regulation of antigen receptor gene rearrangement

V(D)J recombination assembles antigen-specific immunoglobulin and T-cell receptor variable region genes from germline V, D, and J segments during lymphocyte development. Regulation of this site-specific DNA rearrangement process occurs with respect to the cell type and stage of differentiation, orde...

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Detalles Bibliográficos
Autores principales: Spicuglia, Salvatore, Zacarias-Cabeza, Joaquin, Pekowska, Aleksandra, Ferrier, Pierre
Formato: Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948343/
https://www.ncbi.nlm.nih.gov/pubmed/20948810
http://dx.doi.org/10.3410/B2-23