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NKX2-3 Transcriptional Regulation of Endothelin-1 and VEGF Signaling in Human Intestinal Microvascular Endothelial Cells

BACKGROUND: NKX2-3 is associated with inflammatory bowel disease (IBD). NKX2-3 is expressed in microvascular endothelial cells and the muscularis mucosa of the gastrointestinal tract. Human intestinal microvascular endothelial cells (HIMECs) are actively involved in the pathogenesis of IBD and IBD-a...

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Detalles Bibliográficos
Autores principales: Yu, Wei, Hegarty, John P., Berg, Arthur, Chen, Xi, West, Gail, Kelly, Ashley A., Wang, Yunhua, Poritz, Lisa S., Koltun, Walter A., Lin, Zhenwu
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102722/
https://www.ncbi.nlm.nih.gov/pubmed/21637825
http://dx.doi.org/10.1371/journal.pone.0020454