Elongator Complex Influences Telomeric Gene Silencing and DNA Damage Response by Its Role in Wobble Uridine tRNA Modification

Elongator complex is required for formation of the side chains at position 5 of modified nucleosides 5-carbamoylmethyluridine (ncm(5)U(34)), 5-methoxycarbonylmethyluridine (mcm(5)U(34)), and 5-methoxycarbonylmethyl-2-thiouridine (mcm(5)s(2)U(34)) at wobble position in tRNA. These modified nucleoside...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Changchun, Huang, Bo, Eliasson, Mattias, Rydén, Patrik, Byström, Anders S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164696/
https://www.ncbi.nlm.nih.gov/pubmed/21912530
http://dx.doi.org/10.1371/journal.pgen.1002258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164696/
https://www.ncbi.nlm.nih.gov/pubmed/21912530
http://dx.doi.org/10.1371/journal.pgen.1002258

Ejemplares similares