DNA Resection at Chromosome Breaks Promotes Genome Stability by Constraining Non-Allelic Homologous Recombination

DNA double-strand breaks impact genome stability by triggering many of the large-scale genome rearrangements associated with evolution and cancer. One of the first steps in repairing this damage is 5′→3′ resection beginning at the break site. Recently, tools have become available to study the conseq...

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Detalles Bibliográficos
Autores principales: Tan, Frederick J., Hoang, Margaret L., Koshland, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315486/
https://www.ncbi.nlm.nih.gov/pubmed/22479212
http://dx.doi.org/10.1371/journal.pgen.1002633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315486/
https://www.ncbi.nlm.nih.gov/pubmed/22479212
http://dx.doi.org/10.1371/journal.pgen.1002633

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